Because there are so few selective herbicides registered for use in lettuce, it is necessary to kill as many weeds as possible prior to planting. Fumigants, flooding and solarization will kill weed seeds but it will be necessary to germinate them first for most herbicides to be effective. Almost any herbicide can be used preplant that is registered for “fallow” conditions as long as the preplant and preharvest intervals are observed. The following table summarizes the most commonly used herbicides for ground preparation in lettuce.